The Salk Polio Vaccine Trials in Ann Arbor: How Michigan Became the Epicenter of a Medical Breakthrough

On April 12, 1955, Dr. Thomas Francis Jr. announced from the Rackham Auditorium that the Salk polio vaccine was ‘safe, effective, and potent.’ Drawing on contemporary press releases, newspaper headlines, and eyewitness accounts, this article reconstructs the atmosphere of hope and fear that surrounded the largest medical field trial in American history.

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